In this episode, we talk a little technical and summarise:
· The major hormones involved in regulating blood sugar and metabolism
· The original semaglutide SUSTAIN Phase 3 trial in diabetes patients and its expansion to use for weight loss
· The general mechanisms of GLP-1 inhibitors
· Why discontinuing medicine long-term can be desirable for non-diabetics and what happens after
Links:
https://zatonski.substack.com/p/glp-1s-for-weight-loss?utm_source=publication-search
https://dom-pubs.onlinelibrary.wiley.com/doi/epdf/10.1111/dom.14725
https://pmc.ncbi.nlm.nih.gov/articles/PMC7064975/
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